中国的机器人外科学杂志 | ISSN 2096-7721 | CN 10-1650/R

联合保留最大尿道长度和膀胱颈的尿道重建术在机器人前列腺癌根治术早期尿控中的应用

Urethral realignment with maximal urethral length and bladder neck preservation in robot-assisted radical prostatectomy: early urinary continence recovery

作者:曲发军 ,张宗勤 ,吴震杰 ,王林辉 ,崔心刚

1 No. 3 Aug. 2020 DOI: 10.12180/j.issn.2096-7721.2020.03.003 发布日期:2022-08-06
关键词:机器人前列腺癌根治术;膀胱颈保留术;最大尿道长度保留术;早期尿控;局限性前列腺癌

作者简介:

评估使用膀胱颈保留术(Bladder neck preservation,BNP)和最大尿道长度保留术(Maximal urethral length preservation,MULP)进行机器人辅助前列腺癌根治术(Robot-assisted radical prostatectomy,RARP)对 术后早期尿控恢复的治疗意义。方法:回顾性分析 2018~2019 年本中心施行机器人前列腺癌根治术的患者信息,纳 入标准为 Gleason 评分≤ 7(3+4)、≤ cT2c 分期以及 PSA<20ng/ml,排除在磁共振成像显示膀胱颈或前列腺尖部受 累的患者。共有 24 例患者接受联合保留最大尿道长度和膀胱颈的尿道重建术。尿控定义为不穿垫子或只穿一个安 全垫。结果:拔除导尿管后即刻(术后 2 周),以及术后 1 个月、3 个月和 6 个月的尿控率分别为 12(50.0%)、 18(75.0%)、20(83.3%)和 23(95.8%),2 例患者出现尿瘘(8.3%),未见手术切缘阳性病例。结论:对于 Gleason 评分≤ 7 的局限性前列腺癌患者,联合使用 BNP 和 MULP 的尿道重建技术可实现 RARP 术后尿控快速恢复。

To evaluate early recovery of urinary continence after robot-assisted radical prostatectomy (RARP) with urethral realignment using bladder neck preservation (BNP) and maximal urethral length preservation (MULP). Methods: Patients who underwent RARP between 2018 and 2019 owing to prostate cancer with a Gleason score<7 (3+4), ≤ cT2c stage, and prostate-specific antigen level<20ng/ml were investigated. Patients with tumors of the bladder neck or apex on magnetic resonance imaging were excluded. 24 patients in total underwent RARP with BNP and MULP urethral realignment. Continence was defined as wearing no pad (or one). Results: The continence rates were 12 (50%), 18 (75%), 20 (83.3%) and 23 (95.8%) respectively after Foley catheter removed at 2 weeks 1 month, 3 and 6 months after operation. 2 (8.3%) cases were found urine fistula and no positive surgical margin found. Conclusion: Urethral realignment under BNP and MULP can accelerate the continence recovery after RARP in young patients with localized prostate cancer and Gleason score ≤ 7.

稿件信息

收稿日期:2020-02-18  录用日期:2020-04-12 

Received Date: 2020-02-18  Accepted Date: 2020-04-12 

基金项目:国家自然科学基金面上项目(81772747);国家自然科学基金青年科学基金项目(81702501);上海市浦东新区公 利医院人才培养计划资助(拔尖人才,GLRB2019-01);第二军医大学青年启动基金(2016QN22);浦东新区医学学科建设项目: 临床高峰学科 - 泌尿外科(PWYgf2018-03) 

Foundation Item: National Natural Science Foundation of China (81772747); National Natural Science Foundation of China for Youths (81702501); Talent Project of Shanghai Pudong New Area Gongli Hospital (Grant No. GLRB2019-01); The Youth Foundation of Second Military Medical University (2016QN22); Top-level Clinical Discipline Project of Shanghai Pudong (PWYgf2018-03) 

通讯作者:崔心刚,Email:cuixingang@163.com Corresponding 

Author: CUI Xingang, Email: cuixingang@163.com 

引用格式:曲发军,张宗勤,吴震杰,等 . 联合保留最大尿道长度和膀胱颈的尿道重建术在机器人前列腺癌根治术早期尿控中的 应用 [J]. 机器人外科学杂志,2020,1(3):174-179. 

Citation: QU F J, ZHANG Z Q, WU Z J, et al.Urethral realignment with maximal urethral length and bladder neck preservation in robot-assisted radical prostatectomy: early urinary continence recovery[J]. Chinese Journal of Robotic Surgery, 2020, 1 (3):174- 179.

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