探讨机器人辅助单孔腹腔镜根治性前列腺切除术(Single-port Robot-assisted Radical Prostatectomy, spRARP)治疗中高危前列腺癌(Prostate Cancer, PCa)患者的临床应用价值。方法:回顾性分析哈尔滨医科大学 附属第一医院 2021 年 6 月—2022 年 1 月行 spRARP 手术患者的临床资料和围手术期指标,所有患者术前均评估 为中高危 PCa。结果:本研究共纳入 8 例患者,平均年龄为 69.75(50~80)岁,平均体重指数(BMI)为 24.75 (17.96~28.34)kg/m2 ,平均 PSA 为 43.67(8.58~100)ng/ml,Gleason 评分平均为 7(6~8)分。手术均顺利完成, 未发生中转开腹或增加辅助通道。平均手术时间为 219.38(130~290)min,平均出血量 131.25(20~400)ml,术后 均未使用阿片类镇痛药物,术后 7d 拔除导尿管且术后即刻尿控良好。切缘 5 例为阴性,3 例为阳性,术后短期随访(1~ 6 个月)均无漏尿,均无切口部位疼痛及不适感。结论:spRARP 治疗中高危 PCa 安全、可行,该术式具有切口小、 术后恢复快、疼痛小等特点,但其远期疗效仍待进一步验证。
To investigate the clinical application of single-port robot-assisted radical prostatectomy (spRARP) in patients with medium or high-risk prostate cancer (PCa). Methods: Clinical data and perioperative parameters of patients under spRARP for medium or high-risk PCa in the First Affiliated Hospital of Harbin Medical University from June 2021 to January 2022 were collected and analyzed retrospectively. Results: 8 patients were selected in this study, with the average age of 69.75(50-80) years and mean body mass index (BMI) of 24.75(17.96-28.34)kg/m2 . The average PSA was 43.67(8.58-100) ng/ml, and the average Gleason score was 7 (6-8). All surgeries were successfully completed without conversion to laparotomy or adding auxiliary channels. The mean operative time was 219.38 (130-290)min, with an average blood loss of 131.25(20-400)ml. No opiate analgesics were used after operation. The catheter was removed 7 days after operation and immediate postoperative urinary continence was satisfied. Negative margins were found in 5 cases and positive margins in 3 cases. There was no leakage of urine during the short-term followup (1-6 months) after operation, and no pain or discomfort occurred at the incision site. Conclusion: spRARP is safe and feasible in treating moderate or high risk PCa, but further studies should be done to confirm its long-term efficacy.
收稿日期:2022-02-28 录用日期:2022-06-25
Received Date: 2022-02-28 Accepted Date: 2022-06-25
基金项目:哈尔滨医科大学附属第一医院杰出青年医学人才培养资助项目(HYD2020JQ0020) Foundation Item: Youth Medical Talent Cultivation Founding Project of the First Affiliated Hospital of Harbin Medical University(HYD2020JQ0020)
通讯作者:王春阳,Email:435427896@qq.com
Corresponding Author: WANG Chunyang, Email: 435427896@qq.com
引用格式:王越,苏子良,贾光,等 . 机器人辅助单孔腹腔镜根治性前列腺切除术在中高危患者中的应用 [J]. 机器人外科学杂志(中 英文),2022,3(6):451-455.
Citation: WANG Y, SU Z L, JIA G, et al. Application of single-port robot-assisted laparoscopic radical prostatectomy in medium or high-risk prostate cancer[J]. Chinese Journal of Robotic Surgery, 2022, 3(6): 451-455.
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