目的:探讨机器人辅助腹腔镜改良“一体位”根治性肾输尿管切除术及膀胱袖套状切除术治疗上尿路 尿路上皮癌(Upper Tract Urothelial Carcinoma,UTUC)的安全性和可行性。方法:回顾性分析 2021 年 1 月—2021 年 12 月哈尔滨医科大学附属第一医院行 RARNU 术 7 例患者的临床资料,并观察所有患者的围手术期数据和病理 结果。结果:所有患者手术均顺利完成,无围手术期并发症发生。7 例患者手术时间为 235.0(203.5~322.5)min, 术中出血量为 30.0(25.0~50.0)ml,平均随访时间为 4.3 个月,无复发及转移病例。所有患者术后病理诊断均为 UTUC,无切缘阳性,病理分期数据显示:4 例患者为 T3 期,1 例患者为 T1 期,1 例患者为 T2 期,1 例患者为 T4 期。 结论:机器人辅助腹腔镜改良“一体位”治疗 UTUC 的短期疗效是安全、可行的,但其远期疗效有待进一步证实。
Objective: To evaluate the safety and feasibility of single-docking robot-assisted radical nephroureterectomy with bladder cuff excision in the treatment of upper tract urothelial carcinoma (UTUC). Methods: Clinical data of 7 patients who underwent robot-assisted radical nephroureterectomy (RARNU) in the First Affiliated Hospital of Harbin Medical University from January 2021 to December 2021 was retrospectively analyzed, and the perioperative data and pathological results of patients were collected and analyzed. Results: All surgeries were successfully completed without perioperative complications. The median operative time of 7 patients was 235.0 (203.5-322.5) min, with a median intraoperative bleeding volume of 30.0 (25.0-50.0) ml. The average follow-up period after surgery was 4.3 months, and no recurrence or metastasis was found in the follow-up. All patients were pathologically diagnosed as UTUC after surgery. No positive margin was found. Pathological staging data indicated that 4 patients were stage T3, 1 patient was stage T1, 1 patient was stage T2, and 1 patient was stage T4. Conclusion: Robotassisted laparoscopy with modified single-docking technique for UTUC is safe and feasible. However, further studies should be performed to confirm its long-term efficacy.
收稿日期:2022-03-02 录用日期:2022-05-30
Received Date: 2022-03-02 Accepted Date: 2022-05-30
基金项目:哈尔滨医科大学附属第一医院杰出青年医学人才培养资助项目(HYD2020JQ0020) Foundation Item: Youth Medical Talent Cultivation Founding Project of the First Affiliated Hospital of Harbin Medical University(HYD2020JQ0020)
通讯作者:王春阳,Email:435427896@qq.com
Corresponding Author: WANG Chunyang, Email: 435427896@qq.com
引用格式:苏子良,王越,贾光,等 . 机器人辅助腹腔镜改良“一体位”治疗上尿路尿路上皮癌的短期疗效 [J]. 机器人外科学杂志 (中英文),2022,3(6):477-481.
Citation: SU Z L, WANG Y, JIA G, et al. Short-term efficacy of robot-assisted laparoscopy with modified single-docking technique for upper tract urothelial carcinoma [J]. Chinese Journal of Robotic Surgery, 2022, 3(6): 477-481.
[1] Morriss S, Zargar H, Dias B H. Management of the distal ureter during nephroureterectomy for upper tract urothelial carcinoma: a comprehensive review of literature[J]. Urol J, 2021, 18(6): 585-599.
[2] Gross A J, Netsch C, Stolzenburg J U, et al. Upper urinary tract urothelial cell carcinoma[J]. Urologe A, 2020, 59(10): 1265-1274.
[3] 王凯冬 , 曹晓明 , 全辉 . 手术治疗上尿路移行细胞 癌的临床新进展 [J]. 中华腔镜泌尿外科杂志 ( 电子 版 ), 2019, 13(6): 429-432.
[4] Park S Y, Jeong W, Ham W S, et al. Initial experience of robotic nephroureterectomy: a hybrid-port technique[J]. BJU Int, 2009, 104(11): 1718-1721.
[5] Melquist J J, Redrow G, Delacroix S, et al. Comparison of single-docking robotic-assisted and traditional laparoscopy for retroperitoneal lymph node dissection during nephroureterectomy with bladder cuff excision for upper-tract urothelial carcinoma[J]. Urology, 2016. DOI: 10.1016/j.urology.2015.07.070.
[6] Ambani S N, Weizer A Z, Wolf J J, et al. Matched comparison of robotic vs laparoscopic nephroureterectomy: an initial experience[J]. Urology, 2014, 83(2): 345-349.
[7] Kenigsberg A P, Smith W, Meng X, et al. Robotic nephroureterectomy vs laparoscopic nephroureterectomy: increased utilization, rates of lymphadenectomy, decreased morbidity robotically[J]. J Endourol, 2021, 35(3): 312-318.
[8] LaGrange C A, Clark C J, Gerber E W, et al. Evaluation of three laparoscopic modalities: robotics versus three-dimensional vision laparoscopy versus standard laparoscopy[J]. J Endourol, 2008, 22(3): 511-516.
[9] 阮海龙 , 程功 , 陈志贤 , 等 . 机器人辅助单一体位 经腹入路肾输尿管切除 +膀胱袖状切除术治疗 UTUC 的疗效 [J]. 中华泌尿外科杂志 , 2021, 42(11): 810-813.
[10] Zargar H, Krishnan J, Autorino R, et al. Robotic nephroureterectomy: a simplified approach requiring no patient repositioning or robot redocking[J]. Eur Urol, 2014, 66(4): 769-777.
[11] 吴剑平 , 陈明 , 张力杰 . 机器人辅助腹腔镜“一步 法”半尿路切除术 (“大家泌尿网”观看手术视频 ) [J]. 现代泌尿外科杂志 , 2021, 26(2): 104-106.