中国的机器人外科学杂志 | ISSN 2096-7721 | CN 10-1650/R

吊宫联合套扎环阴道封闭在机器人辅助腹腔镜下宫颈癌根治术中的应用效果分析

Clinical efficacy of uterine suspension combining with loop ligature in robot-assisted laparoscopic radical hysterectomy

作者:赵孟玲,王倩,蔡明博,白晶,冯云,郭瑞霞

Vol. 4 No. 5 Oct. 2023 DOI: 10.12180/j.issn.2096-7721.2023.05.005 发布日期:2023-10-19
关键词:宫颈癌;机器人辅助手术;举宫器;根治性子宫切除术;安全性

作者简介:

目的:探讨吊宫法联合套扎环阴道封闭术在机器人辅助腹腔镜下宫颈癌广泛性子宫切除术中的安全 性及有效性。方法:回顾性分析 2017 年 3 月—2021 年 6 月就诊于郑州大学第一附属医院并采用达芬奇机器人辅助 腹腔镜下宫颈癌广泛性子宫切除术的 263 例ⅠA2~ ⅡA2 期宫颈癌患者的临床资料。所有手术均由同一术者进行,按 手术方法不同将患者分为举宫组和吊宫组。举宫组(130 例)术中使用举宫杯,在开放状态下切开阴道壁;吊宫组(133 例)用线结牵拉悬吊子宫,并用套扎环封闭阴道后于线结下方 1.5~2 cm 切开阴道壁。结果:吊宫组平均手术时间短 于举宫组 [(241.71±57.26)min Vs (275.73±88.75)min],术中出血量少于举宫组 [(81.13±61.94)ml Vs (125.88± 122.29)ml],术后住院时间短于举宫组 [(7.62±2.69)d Vs (9.32±4.56)d],术后并发症发生率低于举宫组(4.51% Vs 15.38%),且差异均具有统计学意义(P<0.05);比较两组患者宫旁切除长度、阴道切除长度、淋巴结切除数目、 阴道壁病理切缘、无进展生存期,差异均无统计学意义(P>0.05)。结论:吊宫法联合套扎环阴道封闭术应用于机 器人辅助腹腔镜宫颈癌广泛性子宫切除术有利于术后恢复,且该术式安全、可行,但其远期疗效仍需多中心大样本 长期随访研究进一步证明。

Objective: To explore the safety and efficacy of uterine suspension combining with loop ligature in robotassisted laparoscopic radical hysterectomy. Methods: The clinical data of 263 patients with cervical cancer(IA2~IIA2 stage) who underwent Da Vinci robot-assisted laparoscopic radical hysterectomy in the First Affiliated Hospital of Zhengzhou University from March 2017 to June 2021 were retrospectively analyzed. All surgeries were performed by the same surgeon and divided into the uterus-lifting group and the uterine-suspension group. The uterine manipulator was used in the uterus-lifting group (130 cases) to cut the vaginal wall in the open state. In the uterine-suspension group (133 cases), the uterus was pulled and suspended with suture, and the vagina was incised 1.5-2 cm below the suture after sealing the vagina. Results: The average operative time of the uterine-suspension group was shorter than that of the uterus-lifting group [(241.71±57.26)min Vs (275.73±88.75)min], and the intraoperative blood loss was less than that of the uterus-lifting group [(81.13±61.94)ml Vs (125.88±122.29)ml]. The postoperative hospital stay of the uterine suspension group was shorter than that of the uterus-lifting group [(7.62±2.69)d Vs (9.32±4.56)d], the incidence of postoperative complications was lower than that of the uterus-lifted group(4.51% Vs 15.38%), and the differences were statistically significant (P<0.05). There were no significant differences between the two groups in the length of resected parametriumand vagina, the number of resected lymph nodes, pathological margin of vaginal wall and progression-free survival (P> 0.05). Conclusion: Robot-assisted laparoscopic radical hysterectomy with uterine suspension combining with loop ligature is safe and feasible. However, multi-center, large sample and long-term follow-up studies are still needed to further confirm its long-term efficacy.

稿件信息

收稿日期:2022-04-01  录用日期:2022-11-11 

Received Date: 2022-04-01  Accepted Date: 2022-11-11 

基金项目:河南省中青年卫生健康科技创新领军人才培养项目(YXKC2020012) 

Foundation Item: Young and Middle-aged Talents of Health Science and Technology Innovation in Henan Province (Leader) (YXKC2020012) 

通讯作者:郭瑞霞,Email:tjmgrx@163.com 

Corresponding Author: GUO Ruixia, Email: tjmgrx@163.com 

引用格式:赵孟玲,王倩,蔡明博,等 . 吊宫联合套扎环阴道封闭在机器人辅助腹腔镜下宫颈癌根治术中的应用效果分析 [J]. 机器人外科学杂志(中英文),2023,4(5):423-430. 

Citation: ZHAO M L, WANG Q, CAI M B, et al. Clinical efficacy of uterine suspension combining with loop ligature in robot-assisted laparoscopic radical hysterectomy[J]. Chinese Journal of Robotic Surgery, 2023, 4(5): 423-430.

参考文献

[1] 刘宗超 , 李哲轩 , 张阳 , 等 . 2020 全球癌症统计报告 解读 [J]. 肿瘤综合治疗电子杂志 , 2021, 7(2): 1-14. 

[2] Falconer H, Zahl Eriksson A G, Rudnicki M. Is robotassisted laparoscopy safe for surgical treatment of cervical cancer?[J]. Acta Obstet Gynecol Scand, 2020, 99(1): 5-6.

[3] 李光仪 , 黄浩 , 郑丽丽 , 等 . 腹腔镜手术治疗子宫恶 性肿瘤 8 例分析 [J]. 中华妇产科杂志 , 2001, 36(8): 486-488. 

[4] Ramirez P T, Frumovitz M, Pareja R, et al. Minimally invasive versus abdominal radical hysterectomy for cervical cancer[J]. New Engl J Med, 2018, 379(20): 1895-1904. 

[5] Melamed A, Margul D J, Chen L, et al. Survival after minimally invasive radical hysterectomy for early-stage cervical cancer[J]. New Engl J Med, 2018, 379(20): 1905-1914. 

[6] Machida H, Casey J P, Garcia-Sayre J, et al. Timing of intrauterine manipulator insertion during minimally invasive surgical staging and results of pelvic cytology in endometrial cancer[J]. J Minim Invasive Gynecol, 2016, 23(2): 234-241. 

[7] Kanao H, Matsuo K, Aoki Y, et al. Feasibility and outcome of total laparoscopic radical hysterectomy with no-look no-touch technique for FIGO IB1 cervical cancer[J]. J Gynecol Oncol, 2019, 30(3): e71. 

[8] Ramirez P T, Frumovitz M, Pareja R, et al. Minimally invasive versus abdominal radical hysterectomy for cervical cancer[J]. New Engl J Med, 2018, 379(20): 1895-1904. 

[9] 翟青枝 , 叶明侠 , 于博 , 等 . 达芬奇机器人手术系 统在宫颈癌根治术中学习曲线的研究 [J]. 中国微创 外科杂志 , 2018, 18(5): 422-426. 

[10] 孙嘉敏 , 韩丽萍 , 刘哲颖 , 等 . 达芬奇机器人宫颈 癌广泛子宫切除术的学习曲线研究 [J]. 肿瘤基础与 临床 , 2020, 33(2): 113-117. 

[11] Hwang J H, Yoo H J, Joo J, et al. Learning curve analysis of laparoscopic radical hysterectomy and lymph node dissection in early cervical cancer [J]. Eur J Obstet Gynecol Reprod Biol, 2012, 163(2): 219-223. 

[12] Qiu J, Pankaj P, Jiang H, et al. Laparoscopy versus open distal gastrectomy for advanced gastric cancer: a systematic review and meta-analysis[J]. Surg Laparosc Endosc Percutan Tech, 2013, 23(1): 1-7. [13] PAN S, JIANG W, XIE S, et al. Clinicopathological features and survival of adolescent and young adults with cervical cancer[J]. Cancer Control, 2021. DOI: 10.1177/10732748211051558. 

[14] Jung E J, Byun J M, Kim Y N, et al. Cervical adenocarcinoma has a poorer prognosis and a higher propensity for distant recurrence than squamous cell carcinoma[J]. Int J Gynecol Cancer, 2017, 27(6): 1228- 1236. 

[15] Intaraphet S, Kasatpibal N, Siriaunkgul S, et al. Prognostic impact of histology in patients with cervical squamous cell carcinoma, adenocarcinoma and small cell neuroendocrine carcinoma[J]. Asian Pac J Cancer Prev, 2013, 14(9): 5355-5360. 

[16] 中华医学会妇科肿瘤学分会.宫颈癌微创手术的中国专家共识 [J]. 现代妇产科进展 , 2019, 11(28): 801- 803.

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