目的:对比分析机器人辅助腹腔镜和传统腹腔镜下肾盂成形术治疗儿童肾盂输尿管连接部梗阻 (Ureteropelvic Junction Obstruction,UPJO)的临床疗效,总结机器人辅助腹腔镜肾盂成形术的临床经验及优势。 方法:回顾性分析 2020 年 7 月—2022 年 10 月在山东大学齐鲁医院小儿外科接受机器人辅助腹腔镜肾盂成形术 (Robot-assisted Laparoscopic Pyeloplasty,RALP)(RALP 组,n=22) 及 传 统 腹 腔 镜 肾 盂 成 形 术(Laparoscopic Pyeloplasty,LP)(LP 组,n=48)治疗的患儿的临床资料,并对两组患儿的一般临床资料、手术时间、肾盂输尿管 吻合时间、术中失血量、术后住院天数、住院总费用、术后短期并发症、手术治疗效果等指标进行对比,分析两种 手术方式的优劣。结果:两组术后肾盂前后径(Anteroposterior Diameter,APD)较术前均有明显减小(P<0.001)。 与 LP 组相比,RALP 组的肾盂输尿管吻合时间更短 [(27.95±9.52)min Vs(41.17±8.34)min,P<0.001],住院总 费用更高 [5.05(4.78,5.26)万元 Vs 3.63(3.38,3.84)万元,P<0.001],而两组的手术时间、术中出血量、术后住 院天数、术后并发症发生率、手术前后 APD 差值比较,差异均无统计学意义。结论:机器人辅助腹腔镜肾盂成形术 是治疗儿童 UPJO 安全、有效的手段。与传统腹腔镜肾盂成形术相比,机器人辅助腹腔镜肾盂成形术具有术野清晰、 缝合精准、术中肾盂输尿管吻合时间短、学习曲线短、符合人体工程学等优势,不足之处主要在于其住院费用较高, Trocar 孔瘢痕稍大。
Objective: To compare and analyze the clinical efficacy of robot-assisted and conventional laparoscopic pyeloplasty in the treatment of ureteropelvic junction obstruction (UPJO) in children, and summarize the clinical experience and advantages of robot-assisted laparoscopic pyeloplasty. Methods: A retrospective analysis was performed on the clinical data of children treated with robot-assisted laparoscopic pyeloplasty (RALP group, n=22) and conventional laparoscopic pyeloplasty (LP group, n=48) in the Department of Pediatric Surgery of Qilu Hospital of Shandong University from July 2020 to October 2022. The general clinical data, operative time, ureteropelvic anastomosis time, intraoperative blood loss, postoperative hospital stay, total hospitalization costs, postoperative short-term complications, and surgical treatment effects of the two groups were compared to analyze advantages and disadvantages of the two surgical methods. Results: The postoperative APD (Anteroposterior Diameter) of the two groups was significantly lower than that before surgery (P<0.001). Compared with LP, the time of ureteropelvic anastomosis in children with RALP was shorter [(27.95±9.52)min Vs(41.17±8.34)min, P<0. 001] , and the total cost of hospitalization was higher [50.5(47.8, 52.6) thousand CNY Vs 36.3(33.8, 38.4) thousand CNY (P<0. 001) ], while there were no significant differences in operative time, blood loss, postoperative hospital stay, postoperative complication rate, and APD difference before and after surgery. Conclusion: Robot-assisted laparoscopic pyeloplasty is a safe and effective way to treat UPJO in children. Compared with the conventional laparoscopic pyeloplasty, it has clearer field of vision, more precise suturing, shorter ureteropelvic anastomosis time, shorter learning curve, and more ergonomic position. However, it faces the disadvantages of higher cost of hospitalization and slightly larger scar of the Trocar hole.
收稿日期:2022-12-27 录用日期:2023-04-03
Received Date: 2022-12-27 Accepted Date: 2023-04-03
通讯作者:李爱武,Email:liaiwu@qiluhospital.com
Corresponding Author: LI Aiwu, Email: liaiwu@qiluhospital.com
引用格式:刘慧,范晓晓,李德儒,等 . 机器人辅助腹腔镜与传统腹腔镜下肾盂成形术在治疗儿童肾盂输尿管连接部梗阻中的对 比分析 [J]. 机器人外科学杂志(中英文),2023,4(5):477-484.
Citation: LIU H, FAN X X, LI D R, et al. Comparative analysis of robot-assisted and conventional laparoscopic pyeloplasty in the treatment of ureteropelvic junction obstruction in children [J]. Chinese Journal of Robotic Surgery, 2023, 4(5): 477-484.
[1] Peters C A, Schlussel R N, Retik A B. Pediatric laparoscopic dismembered pyeloplasty[J]. J Urol, 1995, 153(6): 1962-1965.
[2] Szavay P. Laparoscopic Pyeloplasty for Ureteropelvic junction obstruction[J]. J Laparoendosc Adv Surg Tech A, 2021, 31(10): 1214-1218.
[3] LI P, ZHOU H X, CAO H L, et al. Early robotic-assisted laparoscopic pyeloplasty for infants under 3 months with severe ureteropelvic junction obstruction[J]. Front Pediatr, 2025. DOI: 10.3389/fped.2021.590865.
[4] Andolfi C, Adamic B, Oommen J, et al. Robot-assisted laparoscopic pyeloplasty in infants and children: is it superior to conventional laparoscopy[J]. World J Urol, 2020, 38(8): 1827-1833.
[5] Taktak S, Llewellyn O, Aboelsoud M, et al. Robotassisted laparoscopic pyeloplasty versus laparoscopic pyeloplasty for pelvi-ureteric junction obstruction in the paediatric population: a systematic review and meta-analysis[J]. Ther Adv Urol, 2014. DOI: 10.1177/1756287219835704.
[6] 申宵茹 , 杜浩文 , 管哲明 , 等 . 机器人辅助腹腔镜 治疗肾盂输尿管连接部梗阻的临床应用及研究进 展 [J]. 中华小儿外科杂志 , 2022, 43(1): 87-92.
[7] 李泸平 , 张俊杰 , 张胜利 , 等 . 机器人辅助腹腔镜 与传统腹腔镜在儿童肾盂成形术的应用价值 [J]. 中 华小儿外科杂志 , 2022, 43(1): 14-19.
[8] 中华医学会小儿外科分会泌尿外科学组 . 先天性肾 盂输尿管交界处梗阻诊疗专家共识 [J]. 中华小儿外 科杂志 , 2018, 39(11): 804-810.
[9] 何雨竹 , 倪鑫 , 张潍平 . 儿童先天性肾盂输尿管连 接部梗阻性肾积水手术治疗策略研究进展 [J]. 临床 外科杂志 , 2021, 29(6): 501-504.
[10] Esposito C, Autorino G, Castagnetti M, et al. Robotics and future technical developments in pediatric urology[J]. Semin Pediatr Surg, 2021, 30(4): 151082.
[11] Jayakumaran J, Patel SD, Gangrade BK, et al. Roboticassisted laparoscopy in reproductive surgery: a contemporary review[J]. J Robot Surg, 2017, 11(2): 97- 109.
[12] Kassite I, Braik K, Villemagne T, et al. The learning curve of robot-assisted laparoscopic pyeloplasty in children: a multi-outcome approach[J]. J Pediatr Urol, 2018, 14(6): 570.e1-570.e10.
[13] Tam Y H, Pang K, Wong Y S, et al. From laparoscopic pyeloplasty to robot-assisted laparoscopic pyeloplasty in primary and reoperative repairs for ureteropelvic junction obstruction in children[J]. J Laparoendosc Adv Surg Tech A, 2018, 28(8): 1012-1018.
[14] Esposito C, Masieri L, Castagnetti M, et al. Robotassisted vs laparoscopic pyeloplasty in children with uretero-pelvic junction obstruction (UPJO): technical considerations and results[J]. J Pediatr Urol, 2019, 15(6): 667.e1-667.e8.
[15] Dothan D, Raisin G, Jaber J, et al. Learning curve of robotic-assisted laparoscopic pyeloplasty (RALP) in children: how to reach a level of excellence[J]. J Robot Surg, 2021, 15(1): 93-97.
[16] Bowen D K, Lindgren B W, Cheng E Y, et al. Can proctoring affect the learning curve of robotic-assisted laparoscopic pyeloplasty? Experience at a high-volume pediatric robotic surgery center[J]. J Robot Surg, 2017, 11(1): 63-67.
[17] 余小芳 , 刘玮 , 曹增才 , 等 . 分层次多点悬吊技术在腹腔镜肾盂成形术中的应用研究 [J]. 临床小儿外 科杂志 , 2022, 21(4): 370-373.
[18] Braga L H, Pace K, DeMaria J, et al. Systematic review and meta-analysis of robotic-assisted versus conventional laparoscopic pyeloplasty for patients with ureteropelvic junction obstruction: effect on operative time, length of hospital stay, postoperative complications, and success rate[J]. Eur Urol, 2009, 56(5): 848-857.
[19] Silay M S, Danacioglu O, Ozel K, et al. Laparoscopy versus robotic-assisted pyeloplasty in children: preliminary results of a pilot prospective randomized controlled trial[J]. World J Urol, 2020, 38(8): 1841- 1848.
[20] 陈育贞 , 徐哲 , 曾庆兵 , 等 . 达芬奇机器人系统应 用于小儿肾积水的术中配合体会 [J]. 中山大学学报 ( 医学科学版 ), 2017, 38(3): 475-480.
[21] Gargollo PC. Hidden incision endoscopic surgery: description of technique, parental satisfaction and applications[J]. J Urol, 2011, 185(4): 1425-1431.
[22] Hong Y H, DeFoor W R Jr, Reddy P P, et al. Hidden incision endoscopic surgery (HIdES) trocar placement for pediatric robotic pyeloplasty: comparison to traditional port placement[J]. J Robot Surg, 2018, 12(1): 43-47.
[23] 刘宇静 , 刘德鸿 , 周辉霞 , 等 . 隐匿切口法与传统 通道法机器人辅助腹腔镜小儿肾盂成形术的初步 比较 [J]. 微创泌尿外科杂志 , 2018, 7(1): 6-10.
[24] 刘一帆 , 高贺云 , 张文 , 等 . 机器人辅助单孔腹腔 镜下小婴儿肾盂成形术一例 : 国内首例报道 [J]. 机 器人外科学杂志 ( 中英文 ), 2022, 3(2): 140-148.