目的:探讨机器人辅助腹腔镜手术在复杂大子宫切除术中的临床疗效及优势,为临床诊治过程提供 个体化选择。方法:回顾性分析 2021 年 4 月—2023 年 11 月就诊于宁夏医科大学总医院行子宫全切术的 193 例患者 的临床资料,根据术式分为机器人组和腹腔镜组,分别为 82 例和 111 例。根据两组患者的临床资料数据,统计分 析患者一般资料、围手术期指标、并发症情况,以及大子宫人群和巨大子宫人群围手术期指标。结果:机器人组患 者的术中出血量、术中输血率、术后胃肠功能恢复时间、术后住院时间、术后 12 h VAS 评分、术后并发症发生率均 显著优于腹腔镜组,而两组患者在术中并发症发生率和手术时长方面,差异无统计学意义。在大子宫患者中,机器 人组较腹腔镜组术中输血率降低,术后胃肠功能恢复时间缩短。在巨大子宫患者中,机器人组较腹腔镜组手术时长 缩短,术中出血量减少,术中输血率降低,术后胃肠功能恢复时间缩短,术后住院时间增长。结论:机器人辅助腹 腔镜下复杂大子宫切除术不仅可行、安全,而且有助于患者快速康复,值得在临床上进一步推广使用。
Objective: To investigate the clinical efficacy and advantages of robot-assisted laparoscopic hysterectomy for complex enlarged uterus, and to provide individualized options for the clinical diagnosis and treatment decision. Methods: The clinical data of 193 patients who underwent robot-assisted laparoscopic hysterectomy for complex enlarged uterus in the General Hospital of Ningxia Medical University from April 2021 to November 2023 were retrospectively analyzed. They were divided into the robotic group (n=82) and the laparoscopic group (n=111) according to different surgical methods. The general data, perioperative indicators, complications, and perioperative indexes of large and giant uterus population were statistically analyzed. Results: Intraoperative bleeding, intraoperative blood transfusion rate, postoperative gastrointestinal function recovery time, postoperative hospitalization time, postoperative 12 h VAS scores, and postoperative complication rate of patients in the robotic group were significantly better than those in the laparoscopic group. However, there was no statistically significant difference between the two groups in terms of the incidence of intraoperative complication rate and operative time. In patients with large uterus, the robotic group had a lower intraoperative blood transfusion rate and shorter gastrointestinal function recovery time after surgery than the laparoscopic group. In patients with giant uterus, the robotic group showed shorter operative time, less intraoperative bleeding, lower intraoperative blood transfusion rate, shorter gastrointestinal function recovery time after surgery, longer postoperative hospitalization time than the laparoscopic group. Conclusion: Robot-assisted laparoscopic hysterectomy for enlarged uterus is safe and feasible, , and could help patients recover quickly, which is worthy of clinical promotion.
收稿日期:2024-02-01 录用日期:2024-04-19
Received Date: 2024-02-01 Accepted Date: 2024-04-19
基金项目:宁夏回族自治区重点研发计划项目(2023BEG01001)
Foundation Item: Key R&D Plan Progect of Ningxia Hui Autonomous Region (2023BEG01001)
通讯作者:哈春芳,Email:hachunfang@163.com
Corresponding Author: HA Chunfang, Email: hachunfang@163.com
引用格式:李博巍,马少寒,祁馨仪,等 . 机器人辅助腹腔镜手术在复杂大子宫切除术中的应用探讨(附手术视频)[J]. 机器人外 科学杂志(中英文),2024,5(4):626-632.
Citation: LI B W, MA S H, QI X Y, et al. Exploration of robot-assisted laparoscopic hysterectomy for complex enlarged uterus (with surgical video)[J]. Chinese Journal of Robotic Surgery, 2024, 5(4): 626-632.
[1] 马晓欣 , 梁志清 , 向阳 , 等 . 良性子宫疾病子宫切除术手术路 径的中国专家共识 (2021 年版 )[J]. 中国实用妇科与产科杂志 , 2021, 37(8): 821-825.
[2] Committee opinion No 701: Choosing the route of hysterectomy for benign disease[J].Obstet Gynecol, 2017, 129(6): e155-e159. DOI: 10.1097/AOG.0000000000002112.
[3] Desai V B, Xu X. An update on inpatient hysterectomy routes in the United States[J]. Am J Obstet Gynecol, 2015, 213(5): 742-743.
[4] Mendivil A, Holloway R W, Boggess J F. Emergence of robotic assisted surgery in gynecologic oncology: American perspective[J]. Gynecol Oncol, 2009, 114(2 Suppl): S24-S31.
[5] Herron D M, Marohn M, SAGES-MIRA Robotic Surgery Consensus Group. A consensus document on robotic surgery[J]. Surg Endosc, 2008, 22(2): 313-325; discussion 311-312.
[6] Dindo D, Demartines N, Clavien P A. Classification of surgical complications: a new proposal with evaluation in a cohort of 6336 patients and results of a survey[J].Ann Surg, 2004, 240(2): 205-213.
[7] 程兰 , 陈叙 . 产后出血的研究进展 [J]. 国际妇产科学杂志 , 2018, 45(2): 136-140.
[8] 陈春林 , 尹钊红 . 妇产科良性疾病子宫切除途径的选择 [J]. 中 国实用妇科与产科杂志 , 2023, 39(5): 481-484.
[9] Uccella S, Morosi C, Marconi N, et al. Laparoscopic versus open hysterectomy for benign disease in uteri weighing >1 kg: A retrospective analysis on 258 patients[J]. J Minim Invasive Gynecol, 2018, 25(1): 62-69.
[10] Cianci S, Gueli Alletti S, Rumolo V, et al. Total laparoscopic hysterectomy for enlarged uteri: factors associated with the rate of conversion to open surgery[J]. J Obstet Gynaecol, 2019, 39(6): 805-810.
[11] Louie M, Strassle P D, Moulder J K, et al. Uterine weight and complications after abdominal, laparoscopic, and vaginal hysterectomy[J]. AmJ Obstet Gynecol, 2018, 219(5): 1-8.
[12] Chakraborty N, Rhodes S, Luchristt D, et al. Is total laparoscopic hysterectomy with longer operative time associated with a decreased benefit compared with total abdominal hysterectomy?[J]. Am J Obstet Gynecol, 2023, 228(2): 205.e1-205.e12.
[13] Moon A S, Garofalo J, Koirala P, et al. Robotic surgery in gynecology[J]. Surg Clin North Am, 2020, 100(2): 445-460.
[14] 雍圆圆 , 陈华 , 吴丽仙 , 等 . 机器人援助腹腔镜操作在复杂性子 宫切除术中的应用优势 [J]. 宁夏医学杂志 , 2023, 45(1): 39-41.
[15] 陈华 , 祖逸峥 , 马少寒 , 等 . 达芬奇机器人手术在妇科恶性肿瘤 应用中的临床效果分析 [J]. 宁夏医学杂志 , 2023, 45(2): 126-128.
[16] Lim P C, Crane J T, English E J, et al. Multicenter analysis comparing robotic, open, laparoscopic, and vaginal hysterectomies performed by high-volume surgeons for benign indications[J]. Int J Gynaecol Obstet, 2016, 133(3): 359-364.
[17] Chiu L H, Chen C H, Tu P C, et al. Comparison of robotic surgery and laparoscopy to perform total hysterectomy with pelvic adhesions or large uterus[J]. J Minim Access Surg, 2015, 11(1): 87-93.
[18] Herrinton L J, Raine-Bennett T, Liu L, et al. Outcomes of robotic hysterectomy for treatment of benign conditions: influence of patient complexity[J]. Perm J, 2020, 24: 19.035. DOI: 10.7812/TPP/19.035.
[19] Hirano T, Kaneda T, Ozaki H, et al. Angiotensin II, a unique vasoactive agent dissociates myosin light chain phosphorylation from contraction[J]. J Vet Med Sci, 2018, 80(2): 219-224.